Blood Gene Expression Profile Predicts Response to Antipsychotics
نویسندگان
چکیده
منابع مشابه
Blood Gene Expression Profile Predicts Response to Antipsychotics
Antipsychotic drugs are one of the largest types of prescribed drugs and have large inter-individual differences in efficacy, but there is no methodology to predict their clinical effect. Here we show a four-gene blood expression profile to predict the response to antipsychotics in schizophrenia patients before treatment. We sequenced total mRNA from blood samples of antipsychotic naïve patient...
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BACKGROUND Despite the widespread use of antipsychotics, little is known of the molecular bases behind the action of antipsychotic drugs. A genome-wide study is needed to characterize the genes that affect the clinical response and their adverse effects. METHODS Here we show the analysis of the blood transcriptome of 22 schizophrenia patients before and after medication with atypical antipsyc...
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ژورنال
عنوان ژورنال: Frontiers in Molecular Neuroscience
سال: 2018
ISSN: 1662-5099
DOI: 10.3389/fnmol.2018.00073